Interrogating Associations between Polygenic Liabilities and Electroconvulsive Therapy Effectiveness

نویسندگان

چکیده

Electroconvulsive therapy (ECT) is the most effective treatment for severe major depressive episodes (MDE). Nonetheless, firmly established associations between ECT outcomes and biological variables are currently lacking. Polygenic risk scores (PRSs) carry clinical potential but with response in psychiatry seldom reported. Here, we examined whether PRSs disorder, schizophrenia, cross-disorder, pharmacological antidepressant associated effectiveness.

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ژورنال

عنوان ژورنال: Biological Psychiatry

سال: 2022

ISSN: ['1873-2402', '0006-3223']

DOI: https://doi.org/10.1016/j.biopsych.2022.02.157